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Bromelain decreases inflammation and edema when administered intraperitoneally or orally at doses of 510 mg/kg in animals, reducing inflammation and edema due to histamine, carrageenan, dextran, egg albumin, and formalin ( 4.3 Immunomodulatory effects of bromelain The immunomodulatory effects of bromelain are remarkable because this enzyme is capable of both activating and suppressing the immune system

To examine the impact of substances on blood vessel development in vivo , zebrafish embryos or larvae from transgenic lines like Tg (fli1: EGFP) or Tg (flk1: EGFP) are a great choice (Elsayed et al ., 2020

Molecular and Cellular Biochemistry, 400 (1-2), 265-275

Of course, the benefits and side effects will differ slightly for everyone, depending on the dose, age, and other health factors